エステル交換反応
エステル交換反応
Nov 26, 2009
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Organic Reaction Hub on Instagram: "In 1979, M. Yamaguchi et al. reported that a novel procedure for the rapid preparation of esters and lactones under mild conditions via the alcoholysis of the corresponding mixed anhydrides. “The formation of medium- and large-ring lactones from hydroxy acids using 2,4,6-trichlorobenzoyl chloride/DMAP is known as the Yamaguchi macrolactonization”. Condition: 2,4,6-trichlorobenzoyl chloride/DMAP (best reagent), Et3N, in benzene or toluene (high-dilution conditi
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