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  1. Should I Take Spironolactone for Acne? - Cleveland Clinic Health …

    Dec 28, 2022 · Spironolactone works to clear up hormonal acne by lowering androgen hormones in your body. It’s available as a topical treatment and a pill.

  2. Spironolactone for Acne: How Quickly Will It Work? - Verywell Health

    Oct 28, 2025 · Key Takeaways Spironolactone can take up to five months to show its full effect on acne. Females taking spironolactone must use birth control because it can harm a baby. Take …

  3. Efficacy and Safety of Spironolactone in Acne Management

    Apr 4, 2025 · Spironolactone is well tolerated at doses of 25 to 200 mg/d for acne management.

  4. Spironolactone to Treat Acne: What to Know - GoodRx

    Feb 23, 2022 · Spironolactone (Aldactone) is a diuretic (a “water pill”), which means it is a medication that removes fluid from your body through urination. It can be used off-label to treat acne in women …

  5. Oral spironolactone for acne vulgaris in females: Evidence review and ...

    Sep 1, 2025 · In this review, we evaluate the evidence for the efficacy and safety of oral spironolactone in females with acne vulgaris and provide practical recommendations for prescribing.

  6. Spironolactone For Acne: Benefits and Timeline | Wisp

    Jun 11, 2025 · Discover how long spironolactone takes to work for acne and what to expect during treatment. Learn about timelines, effectiveness, and skincare tips.

  7. Spironolactone for Acne: Dosage, Side Effects & Effectiveness

    Dec 5, 2025 · Learn how spironolactone treats hormonal acne in women. Explore clinical studies, dosage recommendations (25-200mg), side effects, and success rates.

  8. Spironolactone for Acne: Practical Strategies for Optimal Clinical ...

    Dec 3, 2025 · While spironolactone can be effective for acne treatment in any age group, it may be most effective for adult women with acne.

  9. Spironolactone for adult acne – read this first! | MDacne

    Mar 13, 2025 · While Spironolactone doesn't cure acne like oral antibiotics or birth control pills, it helps reduce breakouts to a manageable level. Dermatologists typically prescribe it for 6-12 months to …

  10. Spironolactone for Acne: Side Effects, Effectiveness, and Safety

    Jun 1, 2022 · What dermatologists want you to know about taking spironolactone (Aldactone) for acne, including its side effects and how long it takes to see results.