gut.bmj1d
Effect of faecal occult blood screening on mortality from colorectal cancer: results from a randomised controlled trial
Background: Three large randomised trials have shown that screening for colorectal cancer using faecal occult blood (FOB) tests can reduce the mortality from this disease. Two national pilot studies ...
gut.bmj1d
Hepatitis and liver dysfunction with rifampicin therapy for pruritus in primary biliary cirrhosis
Correspondence to: Dr M Prince, Centre for Liver Research, 4th Floor William Leech Building, Newcastle University Medical School, Framlington Place, Newcastle NE2 4HH, UK; Martin.prince{at}ncl.ac.uk ...
gut.bmj2d
Pathology of idiopathic megarectum and megacolon
Background—The aetiology and pathology of both idiopathic megarectum and idiopathic megacolon are unknown. In particular, it is unknown whether there are abnormalities involving enteric nerves or ...
gut.bmj2d
Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways
2 Microbiology and Tumour Biology Centre, Karolinska Institute, Stockholm, Sweden 3 Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden 4 Microbiology and Tumour ...
gut.bmj2d
PTH-28 Elemental formula and LOFFLEX nutrition therapy; an effective but neglected treatment strategy in Crohn’s disease
Introduction Nutrition therapy in treatment of Chron’s Disease (CD) is not adequately highlighted in adult guidelines despite strong evidence supporting its therapeutic efficacy and thus, this option ...
gut.bmj4d
Aspirin is associated with lower risk of pancreatic cancer and cancer-related mortality in patients with diabetes mellitus
Background Patients with type 2 diabetes mellitus (T2DM) have higher pancreatic cancer (PC) risk. While aspirin has chemopreventive effects on digestive cancers, its effect on PC among patients with ...
gut.bmj5d
Pathophysiology of functional dyspepsia
Functional dyspepsia is a symptom complex characterised by postprandial upper abdominal discomfort or pain, early satiety, nausea, vomiting, abdominal distension, bloating, and anorexia in the absence ...
gut.bmj8d
Induction of macrophage efferocytosis in pancreatic cancer via PI3Kγ inhibition and radiotherapy promotes tumour control
Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...
gut.bmj9d
Endoscopic full-thickness plication for the treatment of PPI-dependent GERD: results from a randomised, sham controlled trial
Background The majority of endoscopic antireflux procedures for GERD are cumbersome to use and randomised long-term data are sparse. We conducted such a trial to determine the efficacy and safety of a ...
gut.bmj10d
Accuracy of screening for gastric cancer using serum pepsinogen concentrations
Professor M A Fujino, First Department of Medicine, Yamanashi Medical University, 1110 Shimokato, Tamaho-cho, Nakakoma-gun, Yamanashi 409-38, Japan. BACKGROUND/AIMS The characteristics of pepsinogen ...
gut.bmj11d
Intestinal ganglioneuromatosis and multiple endocrine neoplasia type 2B: implications for treatment
Dr V V Smith, Histopathology, Camelia Botnar Laboratories, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK. Three infants, who presented with intestinal obstruction due to ...
gut.bmj11d
Ambulatory abdominal inductance plethysmography: towards objective assessment of abdominal distension in irritable bowel syndrome
a Department of Medicine, University Hospital of South Manchester, Manchester, UK, b Department of Clinical Engineering, University Hospital of South Manchester, Manchester, UK Dr L A Houghton, ...