And through pathways of nerve connection to other areas of the brain, the response weakens activity of the brain’s decision-making center in the prefrontal cortex. Overcoming addiction usually ...

Self-control is primarily rooted in the prefrontal cortex—the planning, problem-solving, and decision making center of the brain—which is significantly larger in humans than in other mammals.

Damage to the 'medial' region of the prefrontal cortex -- the brain region that helps with planning and achieving goals -- ...

Most scientists agree that categorizing an object—like thinking of a carrot as either a root vegetable or a party snack—is the job of the prefrontal cortex, the brain region responsible for reasoning ...

Researchers at Tulane University have created a first-of-its-kind subcellular map of an area of the brain commonly affected ...

The medial prefrontal cortex is a focus in the study of both issues. The experimental strategies utilize intersectional optogenetic and chemogenetic approaches.