Microsatellite instability (MSI), which results from defects in the DNA mismatch repair system, is an important biomarker in colorectal cancer. While the MSI-high (MSI-H) status predicts response to ...

Werner syndrome ATP-dependent helicase (WRN) is an enzyme involved in DNA replication and repair and has been identified as a synthetic lethality target in tumors with high microsatellite instability ...

The firm is prioritizing development of its anti-DKK1 antibody sirexatamab following promising Phase II results in microsatellite-stable colorectal cancer.

Targeted Oncology provides news, videos, and reviews on the rapidly evolving world of targeted therapies and immunotherapy ...

Cancer care has changed dramatically over the last decade. As opposed to a "one-size-fits-all" approach, treatment today is at an exciting crossroads: precision oncology - therapy directed at the ...

An evaluation of nearly 19,000 patients with metastatic colorectal cancer supported clinical trial data that immunotherapy ...

The study will include two cohorts of breast cancer patients: triple-negative breast cancer and HR-positive, HER2-negative breast cancer.

A panelist discusses how multiple molecular biomarkers beyond BRCA and homologous recombination deficiency (HRD) testing are ...

Mercury, and Rahu in Aquarius whose dasa is running. To conclude, we can expect instability in the current J&K governments.

Singapore's ruling People's Action Party (PAP) has won by a landslide in an election dominated by concerns over the cost of living and the country's future economic stability. Led by Prime ...