Sarcoma is a type of cancer that can appear anywhere in the body and everyday 15 people in the UK are diagnosed with it, ...

“In terms of breast cancer, lung cancer and bowel cancer, it’s very obvious where they come from, whereas the word sarcomas doesn’t really tell you anything,” acknowledges Stradling. “Sarcomas are ...

This valuable study presents a novel approach to enhance the therapeutic potential of mesenchymal stromal cells (MSCs) by genetically modifying their glycogen synthesis pathway, resulting in increased ...

Gastrointestinal stromal tumors, or GISTs, ... GISTs can spread to other parts of the body such as the liver, lungs and peritoneum through the bloodstream or lymphatic system.

Mesenchymal stromal cells (MSCs) are delivered directly into the lungs using a bronchoscope (CIBA method), where they migrate through the alveolar space and interact with immune cells—such as ...

Achieving precise delivery of extracellular vesicles (EVs) to treat pulmonary arterial hypertension (PAH) remains challenging. Here, we propose a strategy using hypoxia-induced and glucuronic acid (GA ...

Influenza can cause acute lung injury. Because immune responses often play a role, antivirals may not ensure a successful outcome. To identify pathogenic mechanisms and potential adjunctive ...

Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer. ... Fig. 6 hMENA11a high ...

Consecutive sections of a representative case of lung adenocarcinoma hMENA 11a negative, showed high stromal FN1, TLS PT and low CXCL13. Right, histograms are relative to the IHC analysis of 94 ...

Targeted therapy for gastrointestinal stromal tumors (GIST) has offered prolonged survival and better disease control compared with historic treatments. According to Alexander Helfand, MD, there is ...

Extracellular vesicles budding from stromal macrophages from the blood circulating in patients with metastatic non-small cell lung cancer to predict clinical outcomes. Daniel L Adams , Martin Joseph ...