After just two days on high-fat diets, researchers observed that certain subtypes of ILC3 immune cells already exhibited reduced IL-22 production. A week into the high-fat diet, all ILC3 subtypes ...

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Innate lymphoid cells (ILC) are an important modulator of immunity in many tissues, including lymphoid tissues, but their spatial information is still scarce. Here, the authors use multiplexed and ...

Methods ILC1, ILC2 and ILC3 cells were determined and characterised by confocal microscopy and flow cytometry in ileal and BM biopsies, in peripheral blood (PB) and SF mononuclear cells obtained from ...

Emerging studies have shown that metabolic regulation plays a crucial role in regulating ILC3 activation and function. However, the role of Liver Kinase B1 (LKB1), a key metabolic regulator, in ...

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Several immune cell subsets that may fulfill this role mainly include Th17 cells and Innate Lymphoid Cell 3 (ILC3), which have been observed in contexts such as allograft rejection, autoimmunity, ...

This is a useful tool for code-less analysis of patterns in cell migratory behaviours in vivo using intravital microscopy data and allows correlation with spatial features of the tumour ...