Tammy Stewart's family has a history of Huntington's disease. Her father and sister both died from it, and now she is caring ...

A decade ago, UB researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington’s disease? They found that HTT is something like ...

The FDA has issued a Breakthrough Therapy tag for AMT-130 as a treatment for Huntington’s disease, a rare neurodegenerative disorder with no FDA-approved disease-modifying therapies. The company ...

One protein mitigates Huntington’s disease while another one exacerbates it by regulating the huntingtin protein’s movement ...

Researchers found that inhibiting GSK-3 led to less defects in the axonal transport process and less neuronal cell death, while inhibiting ERK1 led to more transport problems and more cell death.