While these therapies yield impressive results in melanoma and lung cancer, only about 10% of patients with HNSCC experience durable responses. Tongue squamous cell carcinoma (TSCC), the most ...

While these therapies yield impressive results in melanoma and lung cancer, only about 10% of patients with HNSCC experience durable responses. Tongue squamous cell carcinoma (TSCC), the most ...

In recent years, cell therapies have developed alongside chemotherapy and immunotherapy to become a new pillar in the treatment of patients with blood and lymph gland cancer. In solid tumors ...

The Food and Drug Administration (FDA) has approved Romvimza ™ (vimseltinib) for the treatment of adult patients with symptomatic tenosynovial giant cell tumor (TGCT) for which surgical ...

If you just found out that you or your child has a germ cell tumor, you may have a lot of questions about what it means and what comes next. There are many kinds of germ cell tumors, and only some ...

Dr. William Tap led the development of vimseltinib for tenosynovial giant cell tumor. The U.S. Food and Drug Administration (FDA) has approved vimseltinib (Romvimza TM) for adult patients with a rare ...

For solid tumors, however, the efficacy of CAR T-cell treatments has been limited and progress “more incremental,” Christian Hinrichs, MD, with Rutgers Cancer Institute in New Brunswick ...

The single-cell analysis revealed a diverse range of cell types within the tumor microenvironment (TME), including tumor cells, immune cells, and fibroblasts, with varying proportions across cases.

The researchers created organoids from the tumors of patients with recurrent glioblastoma who underwent surgery as part of a Phase I clinical trial for a dual-target CAR-T cell therapy.

Scientists push CAR T cell therapy beyond blood cancers, unlocking potential for targeting solid tumors with enhanced delivery, resilience, and precision in the face of tough obstacles.

Single-cell genomics is already digging beneath broad averages and uncovering the cellular heterogeneity of tissues. And now, according to a new study from Waseda University and bitBiome ...

Granular Cell Tumors (GCTs), also known as Abrikossoff tumors, are rare neoplasms that typically originate from Schwann cells. These tumors most commonly occur in the head and neck region, ...