Cells once thought passive are now seen as sculptors. Their choreography may explain how tissues form and fail. A new study ...

In 2024, China's first national-level registered clinical study of an iPSC-derived cell therapy for Parkinson's disease—also developed by XellSmart—was approved and initiated, including the first case ...

Latus continues to advance its pipeline of novel AAV capsid variants that target disease-relevant cell types in other regions of the central nervous system (e.g., cortex, cerebellum, spinal cord ...

In this study, using a null Agbl5 allele (Agbl5 M1), we demonstrated that Agbl5 is essential for the development of ependymal cells in cerebral ventricle to maintain the brain homeostasis.

The central nervous system (CNS) ... After injury, ependymal cells displayed minimal activation and demonstrated no significant proliferation or cross-lineage differentiation.

The central nervous system (CNS) ... After injury, ependymal cells displayed minimal activation and demonstrated no significant proliferation or cross-lineage differentiation.

Summary: Spinal cord injuries (SCI) are challenging to treat due to the limited regenerative capacity of the central nervous system.A new study reveals that while ependymal cells in the spinal cord ...

26 Nov 2024. Cryo-EM has solved yet another molecular riddle. In the September 6 Acta Neuropathologica, scientists led by Bernardino Ghetti, Indiana University School of Medicine, Indianapolis, ...

Immunofluorescent images of S100β (red, ependymal cells) in the ependyma of Nestin-Cre and Rgs22 f/f;Nestin-Cre mice at P21. By staining S100β, we assessed the integrity of LV wall in Rgs22 f/f ...

Ependymal cell differentiation is a multi-step process orchestrated by a tightly regulated transcriptional program which is responsible for activating numerous genes that promote amplification and ...