It can be quite complicated to design the antibody (or other affinity molecule) drug conjugate complex in such a way that it retains its stability and, at the same time, is fully soluble. This is ...

our Ly6E-targeting antibody-drug conjugate incorporating our proprietary topoisomerase 1 inhibitor payload, ZD06519. These preclinical findings demonstrate how our therapeutic approaches have the ...

One of these processes is conjugation, which is often referred to as a type of bacterial parasexual reproduction. In this article, we will discuss the mechanism of conjugation and how scientists use ...

An antibody–toxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer immunotherapy. Nature Cancer , 2025; DOI: 10.1038/s43018-025-00919-0 Cite This Page : ...

Pfizer is expanding its collaboration with the start-up PostEra, which applies artificial intelligence to medicinal chemistry. The pharmaceutical giant will pay the smaller firm up to $350 million ...

PCV21 is the first pneumococcal conjugate vaccine candidate with more than 20 serotypes to enter a Phase III clinical trial in infants and toddlers. Sanofi and SK Bioscience announced that they have ...

a potential best-in-class next-generation antibody-drug conjugate (ADC), at the EORTC-NCI-AACR (ENA) Symposium 2024 in Barcelona, Spain, as an oral presentation during the plenary session.

The first patient has been dosed in a trial assessing the peptide-drug conjugate CBX-12 in patients with platinum-resistant or refractory ovarian cancer, according to a press release from Cybrexa ...

The pneumococcal conjugate vaccines that were studied were the PCV10 (GSK) and PCV13 (Pfizer). The saccharide in PCV10 is conjugated to nontypable Haemophilus influenzae protein D, tetanus toxoid ...

Westside Barbell, founded by legendary powerlifter and coach Louie Simmons, is one of the most infamous gyms in the strength training world. Originating in Columbus, Ohio, this hardcore house of ...

Global contract development and manufacturing organization (CDMO), Sterling Pharma Solutions, announced on May 30, 2024 that it has invested $3 million into expanding its integrated antibody-drug ...