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Pierre Fabre Laboratories are pleased to announce the acquisition from Antares Therapeutics, Inc. ("Antares"), a spin-out of ...
"The scale at which we analyzed the amyloid peptides was unprecedented," said Ben Lehner of the Wellcome Sanger Institute.
By analyzing thousands of Aβ42 peptides, the scientists gained a better understanding of how mutations in Aβ affect protein ...
A new large-scale study has mapped the first molecular events that drive the formation of harmful amyloid protein aggregates ...
Scientists have mapped how over 140,000 mutations affect the formation of amyloid beta fibrils, offering an unprecedented look at early events in Alzheimer’s disease.
During a live event, Shuo Ma, MD, PhD, discussed the resistance mutation analysis of patients who had disease progression after receiving pirtobrutinib for BTK inhibitor–pretreated chronic lymphocytic ...
The same three amino acid changes, found in all the independently evolved DSS enzymes, enabled the transition from MTOX to DSS activity, according to the research published in Science. A select ...
“The transition begins when cells acquire an altered or hybrid identity, because of inflammation or damage, that can potentially predispose them to a cancerous state, even without cancer-driving ...
"This work shows a key role for epigenetic memory in the transition to cancer even without a genetic mutation," says Feinberg. "This transition state is probably a normal way that the pancreas ...
Using NGTs to induce mutations that could occur naturally ... it will help us in the green transition, he explains. Ramstein says, "Genomic research and technologies have their part to play ...
aDepartment of General Surgery, The First Affiliated Hospital, Sun Yat- sen University, Guangzhou 510080, PR China bDepartment of Hepatic Surgery, The First Affiliated Hospital, Sun Yat- sen ...
“There are two main types of base editors that can be used to engineer transition mutations (C↔T, G↔A, A↔G, T↔C),” explained Sánchez-Rivera. These are cytosine base editors (CBEs), which enable C–G ...