Maio et al (2022) 46 Pembrolizumab in Microsatellite Instability-High or Mismatch Repair Deficient Cancers: An Updated Analysis From the Phase II KEYNOTE-158 Study Cohort K (any advanced solid tumor ...

Colon cancers with high-frequency microsatellite instability have clinical and pathological features that distinguish them from microsatellite-stable tumors. We investigated the usefulness of ...

Prognostic and Predictive Value of Microsatellite Instability Analysis in Circulating Tumor DNA Using Digital Droplet PCR for Patients With Microsatellite Instability Colorectal Cancers ...

John L. Marshall, MD: Every patient with colon cancer and every physician treating colon cancer needs to know the microsatellite status of all patients. This should be tested in every patient with ...

First-line immunotherapy of microsatellite instability-high metastatic colorectal cancer improved survival compared with chemotherapy. Certain patients with microsatellite stable disease also ...

The collaboration will expand upon Owkin’s machine learning-powered test for determining microsatellite instability status among people with colorectal cancer—using it as a platform to build ...

The NICE appraisal of nivolumab for previously treated metastatic colorectal cancer with high microsatellite instability or mismatch repair deficiency [ID1136] will therefore be suspended.

Please give an overview of microsatellite instability (MSI) status and its applications within oncology. Historically Microsatellite Instability (MSI) has been used to screen for Lynch Syndrome ...

The new Droplet Digital PCR Microsatellite Instability (MSI) RUO assay can be completed in one day on a ddPCR-based platform to quantify the level of MSI present in colorectal tumors. Using either ...

1.1 Offer testing to all people with colorectal cancer, when first diagnosed, using immunohistochemistry for mismatch repair proteins or microsatellite instability testing to identify tumours with ...

Bio-Rad Laboratories, Inc. (CA, USA) recently launched its ddPCR Microsatellite Instability (MSI) Assay, which detects instability in the genome that makes people susceptible to colorectal cancer and ...