Sodium-glucose cotransporter-2 (SGLT2) inhibitors have revolutionized the therapeutic landscape of cardiometabolic and renal diseases. Originally developed to lower blood glucose in type 2 diabetes by ...

A collaborative research team has uncovered a previously unknown mechanism of action of yaku'amide B, a structurally complex peptidic natural product derived from deep-sea sponge found in the waters ...

Researchers at the University of Oulu have identified a previously unknown mechanism in humans that may explain why certain medicines and environmental chemicals disrupt the balance of sex hormones.

Jason Mast is a general assignment reporter at STAT focused on the science behind new medicines and the systems and people that decide whether that science ever reaches patients. You can reach Jason ...

About 40% of East Asians suffer from alcohol intolerance, known as “Asian Flush Syndrome,” caused by an ALDH2 genetic mutation. Beyond facial flushing, this mutation carries serious cardiovascular ...

LITTLE ROCK, Ark. (KNWA/KFTA) — The Arkansas Department of Health says a fourth pediatric case of measles has been confirmed in Arkansas, according to a news release. The ADH said the case was ...

The innate immune system serves as the first line of defense against pathogens, with inflammasome complexes playing a pivotal role in orchestrating the ...

After teasing a new regulatory process for personalized genetic medicines at the end of last year, the FDA today unveiled draft guidance for an approval pathway that could see custom CRISPR therapies, ...

The Food and Drug Administration Monday unveiled the details of a new policy designed to make it easier and quicker for patients with very rare diseases to get cutting-edge treatments. The new ...