One-year data suggest allogeneic stem cell-derived islet-cell therapy could become a future option for those with type 1 ...

Vertex Pharmaceuticals is laying off 125 employees and consolidating their Rhode Island buildings after a failed diabetes ...

This allogeneic human stem cell-derived islet cell therapy is currently being ... on engraftment success here given the nature of VX-264 encapsulation and if a tissue rejection response was ...

Oct. 29, 2024 (GLOBE NEWSWIRE) -- Eledon Pharmaceuticals, Inc. (“Eledon”) (NASDAQ: ELDN) today announced positive data for the first three islet transplant recipients treated with an immunosuppression ...

JDRF, in collaboration with The Leona M. and Harry B. Helmsley Charitable Trust (HCT), announced today that it has finalized a grant in the area of islet cell encapsulation to Dr. Camillo Ricordi, M.D ...

Three main strategies are under investigation to protect the stem cell–derived islets from the patient's immune system: Improved immunosuppressant medications, encapsulation as a physical ...

Preclinical data also demonstrated that primary islets encapsulated with Encellin’s EnCRT may be able to reverse T1D. The new funding will advance a Phase 1 clinical trial evaluating ...

introduced the initial implantable polymer called TRAFFIC (Thread-Reinforced Alginate Fiber For Islets enCapsulation) in 2017. TRAFFIC was specifically designed to be positioned within a patient's ...

created the first implantable polymer in 2017 dubbed TRAFFIC (Thread-Reinforced Alginate Fiber For Islets enCapsulation), which was designed to sit in a patient’s abdomen. In 2021, Ma’s team ...

In 2017, Ma, from Cornell’s College of Agriculture and Life Sciences (CALS), developed the Thread-Reinforced Alginate Fiber For Islets enCapsulation (TRAFFIC), a removable nylon thread implant ...

This technology is protected via three patent applications4. Human islets encapsulated in AdoShell® scaffold maintain, in vitro, a gluco-responsive insulin secretion comparable to naked islets.