One-year data suggest allogeneic stem cell-derived islet-cell therapy could become a future option for those with type 1 ...

Vertex Pharmaceuticals is laying off 125 employees and consolidating their Rhode Island buildings after a failed diabetes ...

Moreover, all 12 showed evidence that the islet cells had grafted and were ... a version called VX-264 in which the cells are encapsulated in a protective device designed to protect them from ...

but VX-264 is an encapsulated therapy. In new data released earlier this month, all six patients treated with VX-880 engrafted islet cells produced insulin and had improved glycaemic control ...

To overcome biological barriers of islet transplantation, encapsulation strategies have been developed and robustly investigated. While islet encapsulation can prevent the need for immunosuppressants, ...

Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling long-term diabetes control without the burden of full immunosuppression.

Registry data on patients with type 1 diabetes mellitus who undergo pancreatic islet transplantation indicate that only 8 percent are free of the need for insulin therapy at one year. All seven ...

Over 500 million people worldwide suffer from diabetes—a disease that contributes to major complications such as stroke, kidney failure, cancer, and Alzheimer's disease. At the heart of this ...

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance, published in ...

At the heart of this condition lies the dysfunction of pancreatic islets, the mini-organs called organoids responsible for regulating blood sugar, in both autoimmune type 1 diabetes and stress ...