The locus coeruleus (LC), a brain region marked by neuromelanin, shows an inverted U-shaped intensity curve across the lifespan, peaking in later middle age and declining after age 60.

Using specialized MRI scans to measure the intensity of neuromelanin, a pigment that gives the locus coeruleus (LC) its blue color, the research team observed an inverted U-shaped curve that ...

China dynamics, and global security impact economic forecasts. Click here to read what investors need to know.

The authors have made two beneficial revisions in this round: (1) acknowledging the insufficient data points supporting the inverted U-shaped curve; (2) attempting to control for practice effects.

2025 outlook, Ladder’s business plan continues to prove effective amid a highly dynamic environment shaped by persistent ... owing in part to an inverted yield curve that persisted for years.

3) The use of a quadratic model allows for either a U-shaped or an inverted U-shaped curve, with a global minimum or maximum, respectively (Chiang and Wainwright, 2005: 129–131). Given the potential ...