December 14, 2010 — Editor's note: During the 1990s, patients in intensive care units (ICUs) routinely received heavy sedation while on mechanical ventilation. More recent studies have shown that ...

More time spent in deep sedation while on mechanical ventilation in the ICU was linked to loss of independent living in ICU patients.

Several studies have assessed the safety and efficacy of dexmedetomidine. A recent randomized controlled trial found that dexmedetomidine reduced ventilator days, delirium, tachycardia, and ...

The results of two randomized trials indicate that among intensive care unit (ICU) patients receiving prolonged mechanical ventilation, use of the sedative dexmedetomidine was not inferior (outcome ...

High proportion of time in deep sedation linked to loss of independent living among patients who lived independently before ICU admission. (HealthDay News) — For mechanically ventilated patients who ...

Please provide your email address to receive an email when new articles are posted on . More than half of older ICU survivors who filled a new sedative prescription filled it again within 6 months of ...

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Use of the sedative dexmedetomidine for critically ill patients resulted in less time on a ventilator and less delirium compared to patients administered a more commonly used drug, according to a ...

The Intensive Care Units (ICUs) we know about are filled with the rhythmic hum of ventilators, keeping patients alive in a seemingly serene state, but reality often masks the horrors of their ...

A low dose of the sedative dexmedetomidine given at night may prevent delirium in critically ill patients, according to new research. A low dose of the sedative dexmedetomidine given at night may ...

We thank Juliane Engel and colleagues and E Alexis Bragg and colleagues for their detailed commentaries on the IsoCOMFORT trial, which emphasise the ongoing challenges related to sedation in ...