Tammy Stewart's family has a history of Huntington's disease. Her father and sister both died from it, and now she is caring ...

A decade ago, UB researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington’s disease? They found that HTT is something like ...

PTC518 showed reduced HTT protein and plasma NfL levels in Huntington's patients, with signals of clinical benefit across ...

Researchers found that inhibiting GSK-3 led to less defects in the axonal transport process and less neuronal cell death, while inhibiting ERK1 led to more transport problems and more cell death.

A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington's disease? They found that ...