(2B) Representative images showing expression, and localization of ZO1 and E-Cadherin proteins at epithelial cell: cell junctions. Image Credit: Newcells Biotech Increased permeability of the ...

Less than a year after garnering the first anti-CLDN18.2 approval in the U.S., Astellas Pharma is not resting on its laurels.

This study reports a role for phosphatidylserine (PtdSer) levels at endoplasmic reticulum/plasma membrane (ER/PM) junctions in the control of epithelial fluid and bicarbonate transport. PtdSer levels ...

This opening article in our miniseries examines the importance of the gut microbiome and its role in influencing cancer risk.

Mechanistic studies revealed that CB1R activation in the gut epithelium triggers the ERK1/2 signalling pathway, which leads to the downregulation of tight junction proteins and a reduction in villus ...

Experts explain the role that the bacteria plays in our gut, and how research suggests supplementing our bodies with it could support our overall health.

We studied altogether 50 samples representing human cervical disease of different grades, together with four samples representing normal squamous epithelium and two from columnar cervical epithelium.

Here, the ways in which enteric bacterial pathogens utilise and impact on the three major physiological functions of the intestinal epithelium are discussed: alterations in the structure and function ...

They found that the precise organisation of the auditory epithelium is driven by specific mechanical forces acting at the boundaries where cells touch each other, called cell-cell junctions. It's like ...

Objective To characterise the molecular structure and function of the epithelial tight junction (TJ) and mechanisms of its dysregulation. Methods Molecular analysis of proteins involved in TJ assembly ...