In a phase 3, randomized trial, we enrolled patients with local or regional cutaneous squamous-cell carcinoma, after surgical resection and postoperative radiotherapy, at high risk for recurrence ...

Background: Pure squamous cell carcinomas (SCC) of the genitourinary (GU) tract are less responsive to chemotherapy with limited therapeutic options for systemic disease. SCCs account for 2-8% of ...

Background: Preclinical data indicated that overexpression of TS correlates with reduced sensitivity to P in antifolate- resistant cell lines. A planned subset analysis of a phase 3 trial (Scagliotti ...