While ependymal cells have long been considered (anecdotally) as the vestige of the neural tube single cell layer that generates the CNS, both their origin and their relationship to other cells ...

PBFT02 continued to demonstrate robust, durable elevation in CSF PGRN levels and improvement in plasma NfL, a disease progression biomarker, compared to natural history Dose 2, 50% lower than Dose 1 ...

There is a pressing need for treatments for neurodegenerative diseases. Hopes have been raised by the prospect of neural stem cell therapy; however, despite intense research activities and media ...

A new study has examined brains affected by PTSD at the single-cell level, uncovering distinct genetic alterations that may ...

20 Jun 2025. Anatomy explorers have charted a new path myeloid cells use to access the brain. On 3 June in Neuron, scientists led by Lindsay Hohsfield and Kim Green, both at the University of ...

Using advanced single-nuclei RNA sequencing (snRNA-seq) and a widely used preclinical model for Alzheimer's disease, ...

A new model suggests that astrocytes might be used in computation, coordinating with neurons and connecting synapses in networks.

Cells once thought passive are now seen as sculptors. Their choreography may explain how tissues form and fail. A new study ...

Gene delivery systems can target specific brain cells, a breakthrough that could lead to treatments for Parkinson's, Alzheimer's and other neurodegenerative diseases.

You wouldn't microwave fish around your worst enemy—the smell lingers both in kitchen and memory. It is one few of us like, ...

Chronic pain affects millions of people in the US. Targeting an oft-overlooked brain receptor could one day offer relief.

EM, researchers elucidated the structure of key receptors integral to fast excitatory synaptic transmission in the rat cerebellum.