When generating novel tailor-made proteins, protein engineers routinely apply the principles of 'Darwinian' evolution ... to increase the thermal stability of enzymes. Enzymatic functions depend ...

The novel enzymes are further improved by extensive saturation mutagenesis and other directed-evolution approaches ... variants with increased stability and containing 11–14 amino acid ...

If your work involves protein or pathway engineering, don’t miss this webinar illustrating the approach that Cellibre, a cellular agriculture company leveraged to significantly accelerate their Design ...

Early successes with this approach primarily improved the stability of enzymes ... further optimization with directed evolution to reach speeds common among natural enzymes.

In comparison to other methods such as directed evolution, rational design is less time ... this strategy to engineer protein-based vaccines, antibodies, and enzymes with high thermal stability and ...