The median life expectancy for cystic fibrosis is now over 30 years, and it is projected that in newborn infants it will become more than 40 years. The identification of the cystic fibrosis gene and ...

Chronic lung diseases, such as idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD), are major leading causes of death worldwide and are generally associated with poor ...

Cystic fibrosis transmembrane conductance regulator (CFTR), a Cl−-ion channel, assembles into dynamic macromolecular complexes. Understanding how these complexes regulate the intracellular ...

Background Clinical trials in cystic fibrosis (CF) have been hindered by the paucity of well characterised and clinically relevant outcome measures. Aim To evaluate a range of conventional and novel ...

Sionna Therapeutics, Inc. has announced the presentation of promising preclinical data at the 48th European Cystic Fibrosis Conference in Milan, showing that its nucleotide-binding domain 1 (NBD1 ...

RALEIGH, N.C. — When he was about 14, Pete Proimos learned a soul-crushing statistic about the cystic fibrosis he’d endured since birth: Patients back then didn’t live much past high school.

Cystic fibrosis (CF) is one of the most common inherited diseases in white Americans—occurring in 1 in every 4,855 births—but mounting evidence suggests that the disease is more common in ...

“Cystic Fibrosis involving your pancreas and what that happens is then you don’t produce enough enzymes and you don’t absorb fat, vitamins and other nutrients that is necessary for you to grow,” says ...

251739 Introduction: Liver fibrosis is a chronic fibrosing hepatic disorder following recurrent injury, characterized by the excessive accumulation of extracellular matrix. Early detection has great ...

It seemed like he became so much healthier overnight. A month after birth, we now have the right treatments, the right team, the right diagnosis. Our son has cystic fibrosis, cystic fibrosis does not ...

Background Despite advances in treatment of cystic fibrosis (CF), pulmonary exacerbations remain common. The aim of this study was to determine if frequent pulmonary exacerbations are associated with ...

Repeated injury to the liver can cause liver fibrosis with end -stage cirrhosis being the 12th leading cause of death in the United States. Earlier stages of liver fibrosis can be reversed with ...