“Cell culture models accurately mimicking the tumor microenvironment is important for studying ... Future efforts should improve the physiological relevance of 3D models by incorporating immune cells, ...

“This immune suppression mechanism is well-known ... Combining spatial transcriptomics and ECM imaging in 3D for mapping cellular interactions in the tumor microenvironment. cels. 2025. doi: 10.1016/j ...

The Incucyte ® Live-Cell Analysis System is a fully automated platform for phase contrast and two-color fluorescence imaging, ...

Dr Olwyn Mahon on how she uses 3D models to understand ... where she developed 3D cancer models and applied spatial multiomics to study extracellular matrix and immune interactions.

Despite the efforts of the scientific community, cancer is still a leading cause of death worldwide. Immunotherapy, a ground-breaking strategy for cancer ...

The tumor microenvironment (TME) consists of a complex mix of cellular and non-cellular components, including immune cells, ...

IO Biotech's first-in-class vaccine performs double duty, killing cancer cells and enhancing the tumor microenvironment. A ...

Since the application of molecular biology in cancer ... microenvironment of supporting cells including stromal cells, such as lung fibroblasts, and tissue resident and transient circulating ...

The tumor microenvironment—the complex environment that surrounds cancer cells—is often deprived of nutrients and oxygen, particularly in hard-to-treat cancers like pancreatic cancer.

TI-CH remodeled the tumor immune microenvironment and accelerated tumor organoid growth, findings that support a role for an aging-related hematologic clonal proliferation in cancer evolution.