The San Francisco 49ers entered their Week 18 finale on the road against the Arizona Cardinals with several starters ruled out. Quarterback Brock Purdy, receiver Deebo Samuel and cornerback Deommodore Lenoir were all ruled out with injuries.

The 49ers will wrap up a massively disappointing season without a number of starters when they face the Cardinals in Week 18.

Christian McCaffrey said Monday he's close to fully recovered from the knee injury that ended his season in snowy Buffalo.

Former Oregon Ducks and current San Francisco 49ers cornerback Deommodore Lenoir does not lack confidence in his game or his team. The 49ers missed the playoffs

Among those listed as “out” Friday by 49ers coach Kyle Shanahan were wide receiver Deebo Samuel (rib/wrist), cornerback Deommodore Lenoir (shoulder), quarterback Brock Purdy (shoulder), tackle Spencer Burford (calf) and defensive end Ronald Beal (ankle).