“Expression tells us what cells do, but regulatory DNA tells us where they come from, how they develop, and which germ layer ...

The latest studies published by The Human Cell Atlas make further progress toward their goal of mapping every human cell type, and these four papers focus on multi-tissue cell analysis. The Human Cell ...

Adipose tissue is increasingly recognised not merely as an inert energy reservoir but as a dynamic endocrine organ intricately involved in whole‐body metabolic regulation. Both white and brown ...

Like a phoenix rising from the ashes, our skin tissue—and in fact many types of epithelial tissue that lines and covers the ...

Spatial biology is a series of techniques with which scientists collect detailed cellular information and examine the positional context of cells in a tissue. Individual cells differentially use their ...

AI and large-scale datasets will unlock new biology learning via spatial omics. Provided byOwkin 37 trillion. That is the number or cells that form a human being. How they all work together to sustain ...

Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers ...

Current high-plex approaches for studying single-cell biology, such as flow cytometry and single-cell RNA sequencing, reveal the cell populations present in a sample but are unable to characterize the ...

Retinoic acid, the active state of Vitamin A, appears to regulate how stem cells enter and exit a transient state central to their role in wound repair. Retinoic acid, the active state of Vitamin A, ...

Molecular profiles that “zoom in” (to reveal the contents of single cells) and “zoom out” (to reveal cell-cell relationships in tissue samples) promise to transform medicine Brain metastases ...

Researchers have developed a method to direct stem cells to form specific structures. By triggering the expression of specific genes in mouse embryonic stem cells, synthetic organizer cells were ...