As a proof of concept, the engineers then used the same system to convert acetyl-CoA into malate, a commercially valuable ...

A peptide bridge is designed to construct a fusion enzyme with electrostatic cofactor channeling, reducing NADPH input by two orders of magnitude or decreasing reaction time threefold with the same ...

Researchers have captured real-time "molecular movies" showing how an enzyme changes shape during catalysis. The study was ...

The research, published in The FEBS Journal, improves understanding of classical homocystinuria, a hereditary metabolic disorder, and proposes new potential therapeutic approaches. This genetically ...

Enzymology is the study of enzymes and enzyme-catalyzed reactions. Enzymes are biological catalysts that accelerate the rate of biological reactions. They can also perform multiple reactions ...

Natural biological systems cannot efficiently convert waste CO₂ or its derivatives into useful building-block chemicals at a scale that can keep pace with rising atmospheric carbon. Engineer a fully ...