Trauma exposure influenced reward system function as well. Individuals with greater childhood trauma showed heightened orbitofrontal cortex activation during reward outcomes, particularly among ...

In this study, the research team applied machine learning to distinguish the molecular signature in the orbitofrontal cortex ... and cognitive functions related to substance use disorders.

Orbitofrontal cortex and hippocampus reinstate representations of causal choices to associate with delayed outcomes, and the frontal pole supports this credit assignment process by maintaining pending ...

Here authors show that in mice, the secondary motor cortex determines it by integrating motor thalamic inputs that promote action based on action values and orbitofrontal inputs that bias to non ...

In this study, the research team applied machine learning to distinguish the molecular signature in the orbitofrontal cortex ... and cognitive functions related to substance use disorders.