People who have syndrome of inappropriate antidiuretic hormone secretion (SIADH) produce excessive amounts of antidiuretic hormones. It leads to the body developing an imbalance of sodium and water.

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

A consistent recent finding has been the strong association between hyponatremia and fractures. Initially, two case control studies reported the association of mild asymptomatic hyponatremia with bone ...

Medically reviewed by Isabel Casimiro, MD, PhDMedically reviewed by Isabel Casimiro, MD, PhD Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a condition in which the body makes too ...

The levels of copeptin in the circulation correlate with those of arginine vasopressin (AVP) Currently available techniques for the measurement of copeptin have advantages over those for AVP in terms ...

The patient noted that she was initiated on naproxen by her primary care physician 2 weeks prior to her presentation. A recently published report describes the case of an 88-year-old female patient ...

Central diabetes insipidus is a rare condition that can cause extreme thirst and a frequent need to pee. It occurs when there isn’t enough antidiuretic hormone (ADH) in your body. Diabetes insipidus ...

Your pituitary is a small gland at the base of your brain. Pituitary disorders develop because of problems with your pituitary gland. A growth (tumor) in or near the pituitary often causes these ...

These agents compete with AVP for the vasopressin type 2-receptor and block the effects of AVP to increase free water absorption. Since these agents lead to increases in free water excretion with ...