The APPLE trial began recruitment in November 2017 and ended in February 2020 (5). It was a randomised, open-label, non-comparative, multicentre, phase II study which enrolled treatment naïve patients ...
Nanopore sequencing offers comparable accuracy to short-read NGS for IGH clonotyping in CLL, with advantages in cost and laboratory footprint. The study confirms reliable somatic hypermutation status ...
Roche's innovative sequencing by expansion (SBX) technology represents a leap forward in next-generation sequencing (NGS), which is playing a vital role in decoding complex diseases like cancer, ...
Capsule endoscopy (CE) and double-balloon enteroscopy (DBE) identify complications beyond the reach of conventional bidirectional endoscopy in patients with persistent symptoms of celiac disease.
In cancer research, scientists primarily use genetic sequencing to collect information from liquid biopsy samples. However, traditional methods only provide information on somatic mutations, which can ...
A combined whole-genome sequencing approach could be used to detect and monitor cancer from liquid biopsies. It is challenging to monitor cancer from liquid biopsies due to the low concentrations of ...
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