Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression. In gynecological malignancies-including ovarian, cervical, and ...

AARS, Alanyl-tRNA synthetase; AKT, protein kinase B; CC, cervical cancer; DCBLD1, discoidin, CUB, and LCCL domain-containing protein 1; EC, endometrial cancer; G6PD ...

During the process of metastasis, tumor cells inevitably encounter the stimulation of various oxidative stressors, resulting in the fluctuation of intracellular reactive oxygen species (ROS) levels.

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating ...

DNA and RNA epigenetics, once thought to be separate, have now been found to work together to fine-tune gene expression. When you purchase through links on our site, we may earn an affiliate ...