Hydrogen sulfide (H 2 S)-based mitochondrial energy metabolism blockade is an attractive tumor therapeutic modality. However, it is limited owing to metabolic plasticity, which allows tumors to shift ...

Dario Vitturi, Ph.D., Assistant Professor, Molecular and Cellular Pathology, has received grant funding to support his project “Kynurenine-dependent redox signaling at the interface between innate and ...

A catalytic approach is developed to overcome the side reactions between sulfur cathodes and carbonate electrolytes. The approach is characterized by the interactions between polysulfides and dual N/O ...

Lung adenocarcinoma (ADC) and squamous cell carcinoma (SCC) are two distinct and predominant types of human lung cancer. IκB kinase α (IKKα) has been shown to suppress lung SCC development, but its ...

Researchers at The University of Texas MD Anderson Cancer Center have discovered that a protein called NF-kappa B-inducing kinase (NIK) is essential for the shift in metabolic activity that occurs ...

New research evaluates bortezomib and carfilzomib in an attempt to understand the causes of neurotoxicity in the former. They found the mitochondrial pathway is likely not the problem. Higher rates of ...