This is a preview. Log in through your library . Abstract Skeletal fragility in the elderly does not simply result from a loss of bone mass. However, the mechanisms underlying the concurrent decline ...

New research has now mapped the unique genetic profile of the skeleton's 'master regulator' cells, known as osteocytes. Research led by the Garvan Institute of Medical Research has for the first time ...

A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the ...

Researchers may be "excyted" to learn that osteocyte cultures are headed to the International Space Station this spring for the first time. With their delivery on the next SpaceX commercial resupply ...

Pascal Buenzli receives funding from The Australian Research Council (project grant DE130101191). Natalie Sims receives funding from the National Health and Medical Research Council and The Australian ...

Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain. Bone metastasis is associated ...

Furthermore, the number of osteocyte dendrites-elongated structures that help in regulation of bone remodeling-was reduced in the mutant mice. Additional genomic analysis of cells obtained from the ...

Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain. Bone metastasis is associated ...