image: A series of amines, including synthetic challenging primary amines were synthesized with highly tolerance of other reducible functional groups. Mechanistic studies from control experiments and ...

DESPITE THEIR FUNDAMENTAL ROLE in chemical and biochemical systems, amides are tough to make. Routes to this functional group usually employ toxic reagents, such as thionyl chloride; require corrosive ...

A new reaction that uses an atypical starting material to create amide linkages could make it easier to prepare peptides and other amide-containing compounds that have been difficult to make until now ...