Intrinsically disordered proteins (IDP) are proteins that lack tertiary structure. They are now being recognized as biologically crucial in both healthy systems and the pathophysiology of various ...

As the importance and prevalence of oligonucleotide therapeutics continue to grow, so does the need for robust characterization methodologies throughout drug development and production. Given the ...

In wood, bound water molecules, located in cell walls, can move to great heights to eventually humidify canopy leaves. Using ...

Fragment-based drug discovery (FBDD) has emerged as a transformative approach in medicinal chemistry by focusing on the identification of small chemical fragments that bind to biologically relevant ...

Fluorinated compounds are increasingly used in medicinal, agricultural, and material science applications. NMR probes and procedures were historically employed to get hydrogen and carbon spectra.

Nuclear magnetic resonance (NMR) is an information-rich technique. However, it requires a higher analyte concentration than all other spectroscopic methods, especially when compared to analytical ...

In this editorial, Enrico Ravera gives an overview of the use of paramagnetic metals in NMR and explains how this can provide crucial information about the structure and dynamics of proteins, nucleic ...

Researchers have achieved a breakthrough in zero-field nuclear magnetic resonance spectroscopy, paving the way towards benchmarking quantum chemistry calculations. What is the structure of a ...

Nuclear magnetic resonance (NMR) spectroscopy could be about to go mobile, thanks to a team of researchers in the US that has shrunk the electronic components needed for the spectroscopic technique ...

ZÜRICH--(BUSINESS WIRE)--Bruker announces the acceptance of a 1.2 GHz Ascend™ Nuclear Magnetic Resonance (NMR) spectrometer at the Swiss High-field NMR Facility, operated jointly by the University of ...