Scientists from Emory University School of Medicine and the University of Pavia, Italy, have determined for the first time the three-dimensional structure of monoamine oxidase B (MAO B) — an enzyme ...

Purpose: The pharmacology, pharmacokinetics, clinical efficacy, and safety of rasagiline are reviewed. Summary: Rasagiline is a novel, investigational propargylamine that irreversibly and selectively ...

As well as causing considerable pain, rheumatoid arthritis (RA) can also trigger neuropsychiatric problems including memory impairment. Scientists have now examined the role of monoamine oxidase-B ...

Inhibiting human monoamine oxidase (MAO)-B to increase the availability of monoamine neurotransmitters is a clinically approved strategy for treating Parkinson’s disease, yet available inhibitors lack ...

Bethesda, MD - A combination of luck and scientific curiosity has produced a mouse lacking two isoenzymes, MAO A and MAO B, that have been linked to violent criminal behavior and Parkinson's disease.

A new highly selective PET imaging agent can detect the presence of overexpressed monoamine oxidase-B (MAO-B) in cognitively unimpaired individuals with high beta amyloid -one of the earliest signs of ...

Miralogx LLC and Mira Pharmaceuticals Inc. have jointly disclosed new cannabinoid analogues acting as monoamine oxidase-A (MAO-A) and/or MAO-B inhibitors reported to be useful for the treatment of ...

People with Parkinson’s disease should be aware that some medications, like certain antipsychotics, can worsen motor symptoms by blocking dopamine receptors. Taking MAO-B inhibitors, a common ...

Influence of multiomics on tumor microenvironment remodeling in locally advanced rectal cancer following neoadjuvant chemoradiotherapy plus immunotherapy. This is an ASCO Meeting Abstract from the ...