A small number of islet encapsulation systems have been applied clinically, all of which have demonstrated good safety profiles, although it is too early to evaluate functional outcomes.

One-year data suggest allogeneic stem cell-derived islet-cell therapy could become a future option for those with type 1 ...

Researchers say nanoparticles could help engineer the spleen – a more promising long-term survival site than the liver – into ...

Encapsulated islet cells is a treatment for type 1 diabetes that is currently undergoing research and development. Encapsulated islet cells can be likened to an advanced form of transplantation but ...

"Our approach to inhibit proinflammatory immune responses with poly(N-vinylpyrrolidone)-tannic acid-encapsulated islets without systemic immunosuppression is a significant advancement toward ...

Encapsulation is the evolution of islet cell transplantation. It is an exciting branch of transplant that could free people with type 1 diabetes from administering insulin for up to years, although it ...

While islet cell transplants allow some diabetics ... known as the NICHE (Neovascularized Implantable Cell Homing and Encapsulation). Similar in size to a US quarter-dollar coin, the flat ...

Preclinical data also demonstrated that primary islets encapsulated with Encellin’s EnCRT may be able to reverse T1D. The new funding will advance a Phase 1 clinical trial evaluating ...

delivered islet cells and immunotherapy directly into the 3D printed neovascularized implantable cell homing and encapsulation (NICHE) device, which they described as akin to a bioengineered pancreas.

created the first implantable polymer in 2017 dubbed TRAFFIC (Thread-Reinforced Alginate Fiber For Islets enCapsulation), which was designed to sit in a patient’s abdomen. In 2021, Ma’s team ...

JDRF, in collaboration with The Leona M. and Harry B. Helmsley Charitable Trust (HCT), announced today that it has finalized a grant in the area of islet cell encapsulation to Dr. Camillo Ricordi, M.D ...