Use of a clinician-facing dashboard combined with a best practice alert helped increase rates of HLA-B*58:01 genetic testing among patients prescribed allopurinol.
Somatic mutations in HLA genes were detected in the tumor data of five patients, and somatic HLA gene loss of heterozygosity was identified in the tumor data of five patients. Complete or partial ...
A multi-institutional study led by a Massachusetts General Hospital (MGH) investigator finds significant racial disparities in the risk that patients being treated for gout will develop a serious, ...
A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication allopurinol in U.S. patients. While the gene HLA-B*58:01 has long ...
A new study led by Profs. Xu Tao and He Shunmin from the Institute of Biophysics of the Chinese Academy of Sciences has revealed how human leukocyte antigen (HLA) genes, central to the immune system, ...
—Researchers provide the most comprehensive genetic synopsis of primary biliary cholangitis to date, identifying 44 risk-associated variants with strong evidence for novel genome-wide significant loci ...
A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication allopurinol in U.S. patients. While the gene HLA-B*58:01 has long ...
Toward a Computable Phenotype for Determining Eligibility of Lung Cancer Screening Using Electronic Health Records Accurate human leukocyte antigen (HLA) typing is an essential step for designing ...
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