PanMAN data structures compress pangenomes massively, encode evolutionary histories, and enable scalable analysis of millions of genomes.

Crops increasingly need to thrive in a broader range of conditions, including drought, salinity, and heat. Traditional plant ...

Genetic variation describes naturally occurring genetic differences among individuals of the same species. This variation permits flexibility and survival of a population in the face of changing ...

Researchers at the University of California have created a novel data structure and compression method that allows ...

A number of studies have highlighted that ethnicity is an important factor influencing the genetic variability of some CYP450 enzymes and that human adaptation could have a role in shaping the genetic ...

Researchers still do not have a comprehensive picture of the factors that influence gene expression in human cancers. Understanding gene expression in cancer is important because it can reveal how the ...

Humans were isolated in southern Africa for about 100,000 years, which caused them to "fall outside the range of genetic variation" seen in modern-day people, a new genetic study reveals. The finding ...

Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

There are a number of C. trachomatis gene products that exhibit variability and may modulate disease severity (Figure 3). The major categories of variable chlamydial gene products and their roles in ...