Full NFL Week 15 picks for every game, with predictions straight-up and against the spread across the board.

SportsLine's advanced model has locked in its NFL bets today from 10,000 simulations

My Week 14 straight-up picks went 10-4 and correctly predicted that the Jaguars and Chargers would score upset wins. That moves my straight-up picks to a 73-27 mark over the past seven weeks. Let’s go for an eighth straight week of 10-plus wins in Week 15.

The Chiefs are in trouble, and according to Geoff Schwartz, it's not going to get better in Week 15. Check out his latest NFL best bets.

Expert Larry Hartstein reveals picks, predictions, analysis for Buccaneers vs. Falcons on 'Thursday Night Football'

A week removed from losing the biggest game of their season, and with rematches against the Packers and Lions on the horizon, the Bears are in prime trap territory. The NFC North may be (likely) out of reach, but an emotional hangover could cost Chicago the playoffs altogether.

A 7-1 MAC team gets 24-point respect here. Wazzu is still out for respect after being left for dead when the Pac-12 dissolved — 28. The Ville — fresh off beating the brakes off Kentucky 41-0 — gets 34. These teams are coin-flip close, but Southern Miss’ steadier hand at QB merits a 15.

Each week, The Oklahoman high school sports staff predicts the score of every high school football game in the state. Here are the picks for Week 15.

The complete 2025 College Football All-America Team, featuring first- and second-team selections and headlined by Vanderbilt QB Diego Pavia, our Player of the Year