Scientists had previously assumed that gene activity is controlled by the binding strength and the proximity of the binding site to the gene. Researchers have now discovered that the DNA segment to ...

Scientists have discovered a new structure inside human cells: a never-before-seen twisted "knot" of DNA. Dubbed the "i-motif," this four-stranded knot looks totally different from the iconic double ...

Researchers have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are ...

A research team has solved the three-dimensional structure of a key protein that helps damaged cellular DNA repair itself. Investigators say that knowing the chemical structure of the protein will ...

Substances known as transcription factors often determine how a cell develops as well as which proteins it produces and in what quantities. Transcription factors bind to a section of DNA and control ...