A double-strand break (DSB) is a type of DNA damage where both strands of the DNA helix are cut or broken at the same location, causing a complete discontinuity in the DNA molecule. Unrepaired or ...
DNA double-strand breaks (DSBs) represent one of the most deleterious forms of genomic insult, challenging the cell’s capacity to maintain integrity and prevent oncogenic rearrangements. Repair of ...
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