From synthetic chromosomes and recoded genomes to next-generation gene therapies and engineered cells, discover how genome-scale engineering is redefining the possibilities of biology while reshaping ...

The human genetic blueprint is deceptively simple. Our genes are tightly wound into 46 X-shaped structures called chromosomes. Crafted by evolution, they carry DNA and replicate when cells divide, ...

Robertsonian chromosomes (ROB) are a type of structurally variant chromosome that is created when two chromosomes fuse together to form an unusual bond. Found commonly in nature, these chromosomes are ...

How did humans evolve brains capable of complex language, civilization, and more? The answer could lie in exceptional DNA. Scientists at UC San Francisco have found that parts of our chromosomes have ...

Human artificial chromosomes (HACs) capable of working within human cells could power advanced gene therapies, including those addressing some cancers, along with many laboratory applications, though ...