Lotus Neuro, a clinical-stage biotechnology company pairing focused ultrasound with leading therapeutic modalities to treat focal neurologic disease, today announced its public launch. Spun out in ...

A team of scientists at Texas Tech University Health Sciences Center (TTUHSC) has published new evidence suggesting that the brain's protective shield—known as the blood-brain barrier (BBB)—remains ...

In a large Australian cohort of adults with hypertension, use of blood-brain barrier-crossing antihypertensive medications ...

A study recently published in Nature has identified a key factor in the age-related breakdown of the blood-brain barrier (BBB) and has demonstrated that this damage may be reversible, potentially ...

“If we want to address BBB dysfunction, we have to have a good human BBB model,” said Ziyuan Guo, a neurobiologist and stem cell scientist at Cincinnati Children's Hospital Medical Center. “The whole ...

Oligonucleotide therapeutics, including antisense oligonucleotides and small interfering ribonucleic acid (RNA), have emerged as powerful tools for regulating gene expression and treating neurological ...

The brain is among the most “immune-privileged” of organs primarily through the highly selective permeability of the blood-brain-barrier (BBB), its minimal lymphatic drainage, the presence of ...

The blood–brain barrier (BBB) is a protective filter that lines the brain's blood vessels and is notoriously hard to penetrate, making the treatment of brain disorders very difficult. Strategies ...

The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been employed ...

MPS II, also called Hunter syndrome, is a rare genetic disease that affects over 2,000 individuals, primarily males, world-wide, and leads to behavioral, cognitive, and physical symptoms ultimately ...