Fibroblasts play a central role in maintaining healthy tissue structures, as well as in the development and progression of ...

reside in bone marrow and continuously produce a variety of blood and immune system cells. Mesenchymal stem cells are the source of new bone, cartilage, and connective tissue cells. Neuronal stem ...

For most soft and hard connective tissues (bone, cartilage, tendon, cornea, blood vessels, and skin) collagen fibrils and their networks function as ECM, the highly organized, three-dimensional ...

The extracellular matrices (ECMs) of connective tissues are crucial for normal development and tissue function, and mutations in ECM genes result in a wide range of serious inherited disorders.