Researchers have created a deep learning pipeline for designing soluble analogues of key protein structures used in pharmaceutical development, sidestepping the prohibitive cost of extracting these ...

Proteins and peptides are the primary functional polymers of medical biochemistry, directing virtually all cellular processes through their structural diversity, catalytic activities and signalling ...

Researchers have been elucidating the structures of complex molecules for more than 100 years using a variety of techniques.

Located at the cellular interface, membrane proteins play critical regulatory roles in the signaling between a cell and its interacting environment, making them popular and ideal drug targets.

Recent research, however, has pointed to a different type of cellular structure that may play an equally important role. Called biological condensates, these structures exist because of differences in ...

Membrane proteins represent more than 60 percent of pharmacological targets against human diseases, making them desirable targets for drug discovery campaigns. But, as this webcast will address, ...

Cell membrane proteins hide secret gateways that can be used to modify cell behavior. This has been demonstrated in a study led by the Hospital del Mar Research Institute and published in Nature ...

Researchers from the National University of Singapore (NUS) have successfully applied cryo-electron microscopy (cryo-EM) to unveil the molecular structures of critical protein machines that transport ...

Proteins designed by artificial intelligence (AI) are being considered for use in treating everything from snakebites to cancer. A Nature Communications paper, out this week, describes how Australian ...

Acting as armor, a scaffold and a communication platform in one, our cells' plasma membrane lies at the heart of many crucial cellular processes. Traditionally, it has been thought to function through ...

A great success for plant research at the Leibniz Institute of Plant Biochemistry (IPB) in Halle: The independent junior research group leader Mariana Schuster has been awarded a highly funded ERC ...

Researchers have shown that the formation of biological condensates affects cellular activity far beyond their immediate vicinity. The results show that they may be a previously missing mechanism by ...