It is also important to try to understand if it is a primary oligopathy or axonopathy in the context of finding relevant in vitro or in vivo model systems for PVL. For example, isolated ...

Justin Skeesuck, who is diagnosed with Multifocal Acquired Motor Axonopathy, and Patrick Gray traveled 500 miles across Spain in 2014. The two wrote about it in a book, "I'll Push You,' out June 2017.

Axonopathy is a case in point. Although there has been renewed interest in the link between axonal swellings and pathological hallmarks of AD, such as neurofibrillary tangles and Aβ aggregates, the ...

Researchers in Germany report widespread spinal cord axonopathy in a mouse model of AD. The damage extends to the white matter and motor neurons, raising the possibility that motor neuron deficits ...

Pathological studies have suggested that ALAS involves primary axonopathy with secondary demyelination. However, the identification of mutations in Colony Stimulating Factor 1 Receptor (CSF1R), ...

The researchers note that astrocytosis, myelinated axonopathy, microvascular injury, perivascular neuroinflammation, and phosphorylated tau protein pathology were found in the post-mortem brains.

Significantly asymmetric or focal signs and symptoms due to toxin exposure are unusual, as most neurotoxins produce a generalized distal axonopathy with initial deficits in the feet, and only ...