Human astrocytic brain tumors select for mutations in the p53 tumor suppressor gene early in malignant progression. p53 is activated upon various kinds of cellular stress leading to apoptosis or cell ...

Your priority in any city-building game is to expand outwards - more roads, more houses, more businesses. Anoxia Station turns that against you. As the leader of a mining operation deep, deep beneath ...

When Frostpunk came out back in 2018, it offered a uniquely grim take on the usual strategy game formula. Similar to the pulpier They Are Billions, Frostpunk brings a level of horror to the genre, ...

San Diego (April 3, 2005) – For a human, mere minutes without oxygen (called anoxia) resulting from cardiac arrest, cerebral stroke or being trapped under water can lead to profound tissue damage and ...

OLIVER Wendell Holmes, ecturing in anatomy to the students at Harvard Medical School, held aloft the skeleton of a female pelvis and delineating the pubic arch, said, "This, gentlemen, is the ...

To study the origins of the Late Ordovician mass extinction (LOME), which might have been partly triggered by marine anoxia, researchers modeled global ocean oxygen conditions using uranium isotopes ...

To the Editor: I found the editorial, "Production of Congenital Abnormalities," in the September 13 issue of the Journal thought provoking and a good summary of the role of experimental teratology in ...

Solid tumors often have an inadequate blood supply, which results in large regions that are subjected to hypoxic or anoxic stress. Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that ...

Anoxia Station is a strategy/management game with a dark atmosphere set in a dystopian past. It's 1988 and humanity fights on, as the Earth's state deteriorates. Your crew is part of an international ...

A new study describes a period of rapid global climate change in an ice-capped world much like the present — but 304 million years ago. Within about 300,000 years, atmospheric carbon dioxide levels ...