Healthy cardiomyocytes (left panel) mainly use fatty acids as their energy source. To produce ATP, fatty acids are first converted into acylcarnitines, which are converted back to fatty-acyl-CoA and ...
Since the 1990s, medicinal chemistry research has demonstrated that replacing benzene rings with bicyclo[1.1.1]pentane derivatives enhances drug properties such as solubility and metabolic stability ...
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